diff --git a/src/Http/Http.Extensions/gen/Microsoft.AspNetCore.Http.RequestDelegateGenerator/DiagnosticDescriptors.cs b/src/Http/Http.Extensions/gen/Microsoft.AspNetCore.Http.RequestDelegateGenerator/DiagnosticDescriptors.cs
index 53842cfcd9ce..298ac3eb4e90 100644
--- a/src/Http/Http.Extensions/gen/Microsoft.AspNetCore.Http.RequestDelegateGenerator/DiagnosticDescriptors.cs
+++ b/src/Http/Http.Extensions/gen/Microsoft.AspNetCore.Http.RequestDelegateGenerator/DiagnosticDescriptors.cs
@@ -125,4 +125,13 @@ internal static class DiagnosticDescriptors
         DiagnosticSeverity.Warning,
         isEnabledByDefault: true,
         helpLinkUri: GetHelpLinkUrl("RDG013"));
+
+    public static DiagnosticDescriptor InvalidAsParametersEnumerableType { get; } = new(
+        "RDG014",
+        new LocalizableResourceString(nameof(Resources.InvalidAsParametersEnumerableType_Title), Resources.ResourceManager, typeof(Resources)),
+        new LocalizableResourceString(nameof(Resources.InvalidAsParametersEnumerableType_Message), Resources.ResourceManager, typeof(Resources)),
+        "Usage",
+        DiagnosticSeverity.Warning,
+        isEnabledByDefault: true,
+        helpLinkUri: GetHelpLinkUrl("RDG014"));
 }
diff --git a/src/Http/Http.Extensions/gen/Microsoft.AspNetCore.Http.RequestDelegateGenerator/Resources.resx b/src/Http/Http.Extensions/gen/Microsoft.AspNetCore.Http.RequestDelegateGenerator/Resources.resx
index ba39a95278ac..a83fbe4a38df 100644
--- a/src/Http/Http.Extensions/gen/Microsoft.AspNetCore.Http.RequestDelegateGenerator/Resources.resx
+++ b/src/Http/Http.Extensions/gen/Microsoft.AspNetCore.Http.RequestDelegateGenerator/Resources.resx
@@ -195,4 +195,10 @@
   <data name="KeyedAndNotKeyedServiceAttributesNotSupported_Message" xml:space="preserve">
     <value>The [FromKeyedServices] attribute is not supported on parameters that are also annotated with IFromServiceMetadata. For more information, please see https://aka.ms/aspnet/rdg-known-issues</value>
   </data>
+  <data name="InvalidAsParametersEnumerableType_Title" xml:space="preserve">
+    <value>Invalid enumerable type</value>
+  </data>
+  <data name="InvalidAsParametersEnumerableType_Message" xml:space="preserve">
+    <value>The enumerable type '{0}' is not supported. For more information, please see https://aka.ms/aspnet/rdg-known-issues</value>
+  </data>
 </root>
diff --git a/src/Http/Http.Extensions/gen/Microsoft.AspNetCore.Http.RequestDelegateGenerator/StaticRouteHandlerModel/EndpointParameter.cs b/src/Http/Http.Extensions/gen/Microsoft.AspNetCore.Http.RequestDelegateGenerator/StaticRouteHandlerModel/EndpointParameter.cs
index 8bea8558fea4..301e1d524d71 100644
--- a/src/Http/Http.Extensions/gen/Microsoft.AspNetCore.Http.RequestDelegateGenerator/StaticRouteHandlerModel/EndpointParameter.cs
+++ b/src/Http/Http.Extensions/gen/Microsoft.AspNetCore.Http.RequestDelegateGenerator/StaticRouteHandlerModel/EndpointParameter.cs
@@ -2,6 +2,7 @@
 // The .NET Foundation licenses this file to you under the MIT license.
 
 using System;
+using System.Collections;
 using System.Collections.Generic;
 using System.Collections.Immutable;
 using System.Diagnostics.CodeAnalysis;
@@ -168,7 +169,7 @@ private void ProcessEndpointParameterSource(Endpoint endpoint, ISymbol symbol, I
             }
             if (symbol is IPropertySymbol ||
                 Type is not INamedTypeSymbol namedTypeSymbol ||
-                !TryGetAsParametersConstructor(endpoint, namedTypeSymbol, out var isDefaultConstructor, out var matchedProperties))
+                !TryGetAsParametersConstructor(endpoint, namedTypeSymbol, wellKnownTypes, out var isDefaultConstructor, out var matchedProperties))
             {
                 if (symbol is IPropertySymbol)
                 {
@@ -454,7 +455,7 @@ private static string GetEscapedParameterName(AttributeData attribute, string pa
         }
     }
 
-    private static bool TryGetAsParametersConstructor(Endpoint endpoint, INamedTypeSymbol type, out bool? isDefaultConstructor, [NotNullWhen(true)] out IEnumerable<ConstructorParameter>? matchedProperties)
+    private static bool TryGetAsParametersConstructor(Endpoint endpoint, INamedTypeSymbol type, WellKnownTypes wellKnownTypes, out bool? isDefaultConstructor, [NotNullWhen(true)] out IEnumerable<ConstructorParameter>? matchedProperties)
     {
         isDefaultConstructor = null;
         matchedProperties = null;
@@ -466,6 +467,12 @@ private static bool TryGetAsParametersConstructor(Endpoint endpoint, INamedTypeS
             return false;
         }
 
+        if (type.Implements(wellKnownTypes.Get(WellKnownType.System_Collections_IEnumerable)))
+        {
+            endpoint.Diagnostics.Add(Diagnostic.Create(DiagnosticDescriptors.InvalidAsParametersEnumerableType, location, parameterTypeString));
+            return false;
+        }
+
         var constructors = type.Constructors.Where(constructor => constructor.DeclaredAccessibility == Accessibility.Public && !constructor.IsStatic);
         var numOfConstructors = constructors.Count();
         // When leveraging parameterless constructors, we want to ensure we only emit for writable
diff --git a/src/Http/Http.Extensions/test/RequestDelegateGenerator/CompileTimeCreationTests.AsParameters.cs b/src/Http/Http.Extensions/test/RequestDelegateGenerator/CompileTimeCreationTests.AsParameters.cs
index ced9bb67a029..a42149b8286a 100644
--- a/src/Http/Http.Extensions/test/RequestDelegateGenerator/CompileTimeCreationTests.AsParameters.cs
+++ b/src/Http/Http.Extensions/test/RequestDelegateGenerator/CompileTimeCreationTests.AsParameters.cs
@@ -50,6 +50,9 @@ static string GetNoContructorsError(Type type)
             static string GetInvalidConstructorError(Type type)
                 => $"The public parameterized constructor must contain only parameters that match the declared public properties for type '{TypeNameHelper.GetTypeDisplayName(type, fullName: false)}'. For more information, please see https://aka.ms/aspnet/rdg-known-issues";
 
+            static string GetEnumerableTypeError(Type type)
+                => $"The enumerable type '{TypeNameHelper.GetTypeDisplayName(type, fullName: false)}' is not supported. For more information, please see https://aka.ms/aspnet/rdg-known-issues";
+
             return new []
             {
                     new object[] { "BadArgumentListRecord", DiagnosticDescriptors.InvalidAsParametersSingleConstructorOnly.Id, GetMultipleContructorsError(typeof(BadArgumentListRecord)) },
@@ -57,6 +60,9 @@ static string GetInvalidConstructorError(Type type)
                     new object[] { "BadArgumentListClassMultipleCtors", DiagnosticDescriptors.InvalidAsParametersSingleConstructorOnly.Id, GetMultipleContructorsError(typeof(BadArgumentListClassMultipleCtors))  },
                     new object[] { "BadAbstractArgumentListClass", DiagnosticDescriptors.InvalidAsParametersAbstractType.Id, GetAbstractTypeError(typeof(BadAbstractArgumentListClass)) },
                     new object[] { "BadNoPublicConstructorArgumentListClass", DiagnosticDescriptors.InvalidAsParametersNoConstructorFound.Id, GetNoContructorsError(typeof(BadNoPublicConstructorArgumentListClass)) },
+                    new object[] { "List<string>", DiagnosticDescriptors.InvalidAsParametersEnumerableType.Id, GetEnumerableTypeError(typeof(List<string>)) },
+                    new object[] { "List<IFormFile>", DiagnosticDescriptors.InvalidAsParametersEnumerableType.Id, GetEnumerableTypeError(typeof(List<IFormFile>)) },
+                    new object[] { "Dictionary<string, string>", DiagnosticDescriptors.InvalidAsParametersEnumerableType.Id, GetEnumerableTypeError(typeof(Dictionary<string, string>)) }
             };
         }
     }
diff --git a/src/Shared/RoslynUtils/WellKnownTypeData.cs b/src/Shared/RoslynUtils/WellKnownTypeData.cs
index 7a4fa428c105..494357b17a3a 100644
--- a/src/Shared/RoslynUtils/WellKnownTypeData.cs
+++ b/src/Shared/RoslynUtils/WellKnownTypeData.cs
@@ -32,6 +32,7 @@ public enum WellKnownType
         Microsoft_AspNetCore_Http_IFormCollection,
         Microsoft_AspNetCore_Http_IFormFileCollection,
         Microsoft_AspNetCore_Http_IFormFile,
+        System_Collections_IEnumerable,
         System_DateOnly,
         System_DateTimeOffset,
         System_IO_Stream,
@@ -146,6 +147,7 @@ public enum WellKnownType
         "Microsoft.AspNetCore.Http.IFormCollection",
         "Microsoft.AspNetCore.Http.IFormFileCollection",
         "Microsoft.AspNetCore.Http.IFormFile",
+        "System.Collections.IEnumerable",
         "System.DateOnly",
         "System.DateTimeOffset",
         "System.IO.Stream",