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diffcyt for longitudinal data #27

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antoine4ucsd opened this issue Dec 25, 2020 · 3 comments
Open

diffcyt for longitudinal data #27

antoine4ucsd opened this issue Dec 25, 2020 · 3 comments

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@antoine4ucsd
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Hello
I am using diffcyt and CATALYST to analyse flow data. Everything is working very well so far.
My dataset is made of samples from individuals who differ by gender but I have several time points for each individual.
Iis there a way to run a DA analyze not only by gender but also accounting for the longitudinal design . The underlying question would be something like : does the clustering evolve differently over time (i.e. aging ) between women and men?
For now, I tried lmer model outside of diffcyt but it would be nice to use your package. if not available, do you have any advices?

Thank you in advance,

@rwanja
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rwanja commented Dec 9, 2024

@antoine4ucsd, did you get a solution for this?

@antoine4ucsd
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no unfortunately

@rwanja
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rwanja commented Dec 9, 2024

Thanks for your quick response!

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